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Scientist, Analytical Development (Molecular & Cell Based Assays)
at Vertex Pharmaceuticals Inc (US)
Boston, MA

Scientist, Analytical Development (Molecular & Cell Based Assays)
at Vertex Pharmaceuticals Inc (US)
Boston, MA

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Description

DESCRIPTION

In June 2019, Vertex announced the establishment of a new research site in the Boston area where research, development, and clinical manufacturing for cell and genetic therapies will be primarily based. Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat-and even cure-several of the diseases Vertex is focused on, including sickle cell disease, Duchenne muscular dystrophy and type 1 diabetes. Further investment in a research site specifically designed to advance these programs will be key to Vertex's continued and sustained leadership in these exciting approaches. At Vertex Cell and Genetic Therapies (VCGT) our research teams will bring together the best biology, technologies and enhanced manufacturing capabilities to ensure we bring these cutting-edge transformative therapies to patients as quickly as possible.

We are looking for a researcher who brings enthusiasm, intellectual curiosity, scientific rigor and a desire to innovate new medicines for patients.

KEY RESPONSIBILITIES

  • Develop analytical methods for release and characterization of AAV gene therapy vectors.
  • Establish molecular and cell-based assay platforms to support rapid advancement of multiple programs.
  • Provide subject matter expertise on method transfers/qualification sat CMO.
  • Establish sample and data management platforms and strategy.
  • Establish product specifications and contribute to regulatory filings.
  • Effectively collaborate with a fully integrated team to facilitate the success of projects.
  • Additional duties and responsibilities as required.

REQUIREMENTS

  • PhD in Biochemistry, Cell & Molecular Biology, Genetics or related discipline and 1 to 3 years experience required. Master's degree and 10+ years experience or Bachelor's degree and 12+ years experience considered.
  • Direct industry experience developing molecular and/or cell-based release and characterization assays is required.
  • Experience working with contract research or manufacturing organizations is preferred.
  • Experience working with viral vectors for gene therapy is a plus.
  • Excellent communication skills with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team.

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