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Associate Medical Director, Translational Medicine
at Vertex Pharmaceuticals Inc (US)
Boston, MA

Associate Medical Director, Translational Medicine
at Vertex Pharmaceuticals Inc (US)
Boston, MA

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The successful candidate will be a strategically minded, hands-on early clinical development expert with the responsibility for overseeing the transition of projects from research into clinic development, and for the strategy for early clinical development for specific diseases. Success depends on the integrity, knowledge, imagination, creativity, skill, diversity and teamwork focus of the candidate. To this end, we strive to create an environment of mutual respect, encouragement and teamwork. The individual will collaborate with talented and dedicated colleagues across R&D.

The Medical Director will:

  • Work closely with other functional experts across the organization
  • Provide medical leadership and translational medicine expertise on cross-functional Project Teams
  • Develop early clinical development plans that are innovative, safe and create a foundation for decision making
  • Be responsible for the medical aspects of Phase I studies throughout development, including development of innovative clinical biomarkers to support decision making

This position will report directly to the Head of Translational Medicine, and be a critical element in Vertex's approach to create an effective bridge between discovery research and clinical development.

Key Responsibilities:

  • Provide clinical and translational leadership to drive the design and interpretation of Phase 1-2a studies, in close collaboration with experts in Clinical Biomarkers and Clinical Pharmacology
  • Work with teams to ensure effective execution of Phase 1-2a studies within the portfolio
  • Responsible in collaboration with Global Patient Safety for safety evaluation in early development programs
  • Support exploratory biomarker efforts to aid in clinical and project decision making
  • Provide clear and timely communication and interpretation of study results to department and organizational governance, functional area experts and development review committees
  • Engage with external academic and industry partners in planning and executing strategy and clinical studies
  • Engage with external scientific and medical experts to bring insight to development programs
  • Work with colleagues across the research and clinical organizations to foster an end-to-end view of drug development, with a focus on improving patient care

Minimum Qualifications :

  • MD or MD/PhD
  • Board certified or eligible in a medical or pediatric subspecialty preferred
  • At least 2 years of early clinical development experience in an industry setting
  • Demonstrated experience with design, execution, and analysis of Phase 1-2a clinical studies
  • Effective at building alliances across functions, based on end-to-end drug development thinking and experience
  • Excellent interpersonal communication skills, able to drive collaborations across a matrixed organization

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